Febee Louka
Education
Ph.D. in Analytical (electrochemistry/Medicinal Chemistry], 2004
Ohio University, Athens, OH 45701
Thesis title: 鈥淚nterdependence of Endothelium Dysfunction and the Lifespan of the Cardiovascular System鈥 supervised by Prof. Tadeusz Malinski
M.Sc. (Physical Organic Chemistry), 1996
Alexandria University, Alexandria, Egypt
B.Sc. (Chemistry), 1985
Alexandria University, Alexandria, Egypt
Student Research/Collaboration
- Synthesis of polynuclear Cu(II), Co(II), Mn(II), and Ni(II) complexes used in the DNA cleavage and anticancer.
- Monitoring the environmental pollution caused by chlorinated hydrocarbons and petroleum hydrocarbons in biota and sediment samples using gas chromatography technique. [Certified Trainee by Marine Environment Laboratories (Monaco) International Atomic Energy Agency] 1992-1998.
- Extraction and removal of pollutants from environmental samples and removal of oil spills from environmental systems.
- Fabrication of microsensors for direct electrochemical measurements of nitric oxide, superoxide and peroxynitrite in biological samples from rats, mice and rabbits.
- Synthesis of surfactants that can be used for preventing pesticides and polycyclic aromatic hydrocarbons from penetrating the soil layer and reach the plants roots.
- Synthesis of porphyrin analogs and metal complexes that can be used as coatings for microsensors.
- Dye removal using ecofriendly adsorbents.
- Extraction and purification of 尾-carotene and ascorbic acid from different types of algae. Characterization of these antioxidants using high performance liquid chromatography and spectrophotometric techniques.
- Hands on GC, GC-MS, Atomic absorption, ICP, and UV-vis instruments.
Publications
- Wiemer, G.; Dobrucki, L. W.; Louka, F. R.; Malinski, T. Heitsch, H., AVE 0991, a Nonpeptide Mimic of the Effects of Angiotensin-(1-7) on the Endothelium. Hypertension 2002, 40, 847-52.
- Balbatun, A.; Louka, F. R.; Malinski, T. Dynamics of Nitric Oxide Release in the Cardiovascular System. Acta Biochimica 2003, 50(1), 61-67.
- Massoud, S. S.; Jeanbatiste, R. R.; Nguyen, T. M.; Louka, F. R.; Gallo, A. A., 鈥淐obalt(III) Complexes of Tripod Amines. Kinetics of Aquation of Dichloro[N-(2aminoethyl)-N,N-bis(3 aminopropyl)amine]cobalt(III) Ion鈥. J. Coord. Chem. 2007, 60, 2409-2419.
- Mautner, F. A.; Vicente R.; Louka, F. R.; Massoud, S. S. 鈥淒inuclear Fumarato- and Terephthalato-bridged Copper(II) Complexes. Structural Characterization and Magnetic Properties鈥. Inorg. Chim. Acta, 2008, 361(5), 1339-1348.
- Massoud, S. S.; Mautner, F.A.; Vicente, R.; Louka, F. R. 鈥淪quarato-metal(II) Complexes. Part 3: 渭1,3- (trans) vs. 渭1,2- (cis) bonding in Squarato-bridged Dinuclear Copper(II) and Nickel(II) Complexes dreived from Polypyridyl Amines鈥. Eur. J. Inorg. Chem. 2008, 23, 3709 鈥 3717.
- Louka, F. R.; Mautner, F. A.; Vicente, R.; Massoud, S. S. 鈥溛2-Oxalato-bridged Tricopper(II) Complex Derived from 1,4,8,12-Tetraazacyclopentadecane.Synthesis, Structure and Magnetic Characterization鈥. Inorg. Chem. Commun. 2008, 11(4), 438 441.
- Mautner. F. A.; Louka, F. R.; LeGuet, T.; Massoud, S. S. 鈥淧seudohalide Copper(II)Complexes Derived from Polypyridyl Ligands. Synthesis and Characterization鈥. J. Molecular Struct. 2009, 919, 196鈥203.
- Xu, W.; Louka , F. R.; Doulain, P. E.; Landry, C. A.; Mautner, F. A.; Massoud, S. S. and 鈥淗ydrolytic Cleavage of DNA Promoted by Cobalt(III)-Tetraamine Complexes. Synthesis Characterization of Carbonatobis[2-(2-pyridylethyl)]-(2
pyridylmethyl)aminecobalt(III) Perchlorate鈥. Polyhedron 2009, 28, 1221鈥1228. - Massoud, S. S.; Louka, F. R.; Mikuriyab, M.; Ishidab, H.; Mautner. F. A. "Dicyanamido鈥 metal(II) complexes. Part 3: Hydrolysis of the dicyanamide into amidocyanamide". Inorg. Chem. Commun. 2009, 12(5), 420-425.
- Mautner. F. A.; Louka, F. R.; Massoud, S. S. 鈥淪tructural characterization of some oxalato-bridged copper(II) and nickel(II) complexes". J. Molecular Struct. 2009, 921(1-3), 333-340.
- Mautner, F. A.; Masahiro Mikuriya, M., Ishida, H.; Louka, F. R.; Humphrey, J. W.;
- Massoud, S. S., 鈥淒icyanamido-Metal(II) Complexes. Part 4. Synthesis, Structure and Magnetic Characterization of Polynuclear鈥 Inorg. Chim. Acta 2009, 362(11), 40734080.
- Mason R. P.; Kubant, R.; Jacob, R. F.; Malinski, P., Huang, X.; Louka, F. R.; Borowiec, J.; Mizuno, Y.; Malinski, T. 鈥淟oss of Arterial and Renal Nitric Oxide Bioavailability in Hypertensive Rats with Diabetes: Effect of 尾-Blockers鈥 American Journal
Hypertension 2009, November 22(11), 1160-1166. - Mautner, F. A.; Louka, F. R.; Gallo, A. A., Saber, M. R., Burham, N. B., Albering, J. H.; Massoud, S. S. 鈥淭hiocyanato-Cu(II) Complexes Derived from Tridentate Amine Ligands and from Alanine鈥 Transition Met. Chem. 2010, 35(5), 613- 620.
- Mautner, F. A.; Albering, J. H.; Vicente, R.; Louka, F. R.; Gallo, A. A.; Massoud, S. S. 鈥淐opper(II) Complexes Derived from Tripodal Tris[(2-ethyl-(1-pyrazolyl)]amine鈥. Inorg. Chim. Acta 2011, 365(1), 290-296. http://dx.doi.10.1016/j.ica.2010.09.030
- Massoud, S. S.; Louka, F. R.; Nguyen, T.L.; Mikuriya, M.; Albering, J. H.; Mautner, F. A. 鈥淪tructural and Magnetic Characterization of 1-D Copper Complexes Constructed from Pyrazole-3,5- dicarboxylate Bridging Multi Cu(II) Centers鈥 Inorg. Chim. Acta 2011, 366(1), 394-398. http://dx.doi.10.1016/j.inoche.2011.02.011
- Massoud, S. S.; Mautner, F. A.; Louka, F. R.; Demeshko, S.; Dechert, S.; Meyer, F., 鈥淒iverse Coordination of Polynuclear Copper(II) Complexes Constructed from Benzene Tetracarboxylate鈥 Inorg. Chim. Acta, 2011, 370, 435-443. http://dx.doi.10.1016/j.ica.2011.02.019
- Mautner, F. A.; Albering, J. H.; Corbella, M.; Louka, F.R.; Massoud, S. S. 鈥淎 Unique Unit Cell Containing Simultaneous Doubly and Triply Copper(II) Complexes Bridging by 2,4-Pyridine Dicarboxylate. Synthesis, Structural Characterization and Magnetic Properties鈥 Inorg. Chem. Commun., 2011, 14, 702-705. http://dx.doi.10.1016/j.inoche.2011.02.011
- Louka, F. R.; Spell, M. L.; Grebowicz, J.; Albering, J. H.; Mautner, F. A.; Massoud, S.S. 鈥淐oordination Chemistry of 1,4-Bis[bis(2-pyridylmethyl)aminomethyl]benzene with Copper(II)鈥 J. Mol. Struct., 2011, 995, 103-108. http://dx.doi.10.1016/j.molstruc.2011.03.066
- Massoud, S. S.; Louka, F. R.; Xu, W.; Perkins, R.; Vicente, R.; Albering, J. H.; Mautner, F. A., 鈥淒NA Cleavage by Structurally Characterized Dinuclear Copper(II) Complexes Based on Triazine鈥 Eur. J. Inorg. Chem., 2011, 3469-3479. http://dx.doi.10.1002/ejic.201100157
- Mason, R. P.; Jacob, R. F.; Kubant, R.; Jacoby, R.; Louka, F. R.; J. Corbalan, J.; Malinski, T. 鈥淓ffects of Angiotensin Receptor Blockers on Endothelial Nitric Oxide Release 鈥 The Role of eNOS Variants鈥 Br. J. Clin. Pharmacol. 2012, 74(1), 141-6. doi: 10.1111/j.1365-2125.2012.04189. x. 21. Louka, F. R.; Nguyen, T. L.; Albering, J. H.; Mautner, F. A.; Massoud, S. S. 鈥淯nprecedented formation of a doubly bridged 渭-peroxo-渭- pyrazolyldicarboxylatodicobalt(III) complex鈥. Inorg. Chem.Commun. 2012, 15, 269271.
- Louka, F. R.; Stewart, A. D.; Regel, E.; Mautner, F. A.; Demeshko, S.; Meyer, F.; Massoud, S.S., 鈥淪quarato-Metal(II) Complexes: Part 5. Polynuclear Copper(II) Complexes Bridged by Squarate and Croconate Dianions鈥. Inorg. Chem. Commun. 2012, 22, 60鈥64.
- Massoud, S. S.; Louka, F. R.; Obaid, Y. K Vicente, R.; Ribas, J; Fischer, R. C.; Mautner, F. A. 鈥淢etal ions directing the geometry and nuclearity of azido-metal(II) complexes derived from bis(2-(3,5-dimethyl-1H-pyrazol-1-yl)ethyl)amine鈥 Dalton Transactions 2013, 42, 3968-3978. http://dx.doi:10.1039/C2DT32540C.
- Mautner, F. A.; Louka, F. R.; Hofer, J.; Spell, M.; Lef猫vre, A.; Guilbeau, A. E.; Massoud, S. S. 鈥淥ne-Dimensional Cadmium Polymers with Alternative di(EO/EE) and di(EO/EO/EO/EE) Bridged Azide Bonding Modes鈥. Crystal Growth & Design, 2013, 13 (10), 4518鈥4525.http://dx.doi.org/10.1021/cg400998r
- Massoud, S. S.; Perkins, R.; Louka, F. R.; Xu, W.; Roux, A, L; Dutercq, Q; Fischer, R. C.; Mautner, F. A.; Handa, H.; Hiraoka, Y.; Kreft, G. L.; Bortolottoe, T.; Terenzi, H. 鈥淓fficient hydrolytic cleavage of plasmid DNA by chloro-cobalt(II) complexes based
on sterically hindered pyridyl tripod tetraamine ligands: synthesis, crystal structure and DNA cleavage鈥 Dalton Transactions, 2014, 43, 10086鈥10103. - Mautner, F. A.; Mikuriya, M.; Naka, N.; Louka, F. R.; Massoud, S. S. 鈥淏onding 渭1,3- (trans) vs 渭1,2- (cis) in squarato-bridging dinuclear copper(II) complexes derived from pyridyl amine ligands鈥. Polyhedron, 2015, 85, 110鈥116. http://dx.doi:10.1016/j.poly.2014.08.040
- Massoud, S. S.; Louka, F. R.; David, R. N.; Dartez, M. J.; Nguyn, Q. L.; Labry, N. J. Fischer, R. C.; Mautner, F. A.; 鈥淔ive-coordinate metal(II) complexes based pyrazolyl ligands鈥 Polyhedron, 2015, 90, 258鈥265.
- Massoud, S. S.; Louka, F. R.; Abu-Elhassan, M. A.; Vicente, R.; Mautner, F. A. 鈥淢agneto-structural properties of carbonato-bridged copper(II) complexes. Fixation of atmospheric CO2鈥 New J. Chem. 2015, 39, 5944-5952.
- Massoud, S. S.; Louka, F. R.; Mautner, F. A. 鈥淧olynuclear and Polymeric SquaratoBridged Coordination Compounds鈥 Cryst. Eng. Comm. 2015, 17, 7604-7617.
- Massoud, S. S.; Junk, T.; Louka, F. R.; Herchel, R.; Travnicek, Z.; Fischer, R.; Mautner, F. A. 鈥淪ynthesis, structure and magnetic characterization of dinuclear copper(II) complexes bridged by bicompartmental phenolate鈥 RSC Adv. 2015, 5,
87139-87150. - Massoud, S. S.; Louka, F. R.; Gazzaz, M. A.; Henary, M. M.; Fischer R. C.; Mautner, F. A. 鈥淧olynuclear copper(II) complexes bridged by polycarboxylates of aromatic and N-heterocyclic compounds鈥 Polyhedron 2016, 111, 45-52. Herchel, R.; Dvo艡谩k, Z.; Tr谩vn铆膷ek, Z.; Mikuriyab, M.; Louka, F. R.; Mautner, F. A.; Massoud, S. S. 鈥淢assoud 鈥淐obalt(II) and copper(II) covalently and non-covalently dichlorido-bridged complexes of an unsymmetrical tripodal pyrazolylpyridyl amine ligand: structures, magnetism and cytotoxicity鈥 Inorg. Chim. Acta 2016, 451, 102110.
- Satbhai, K. M.; Louka, F. R.; Klerks, P. L. 鈥淚ndividual and combined effects of petroleum hydrocarbons phenanthrene and dibenzothiophene on reproductive behavior in the amphipod Hyalella azteca鈥 Journal Water, Air & Soil Pollution 2017, 228: 91. DOI 10.1007/s11270-017-3276-x
- Massoud, S. S.; Louka, F. R.; Mautner, F. A. 鈥淪tructural characterization of metal(II) thiocyanato complexes derived from bis(2-(H-pyrazol-1-yl)ethyl)amine鈥 Polyhedron 2017, 124, 237-242.
- Massoud, S. S.; Williams, G. F.; Louka, F. R.; Henary, M. M.; Herchel, R.; Tr谩vn铆膷ek, K.; Fischer, R. C. Mautner, F. A. 鈥淐roconato-bridged copper(II) complexes. Synthesis, structure and magnetic characterization鈥 New J. Chem., 2017, 41, 3846
3856. http://dx.doi:10.1039/C6NJ03943J - Louka, F. R.; Osman, S. Y.; Terracina, T.; Khamidullina, N. 鈥淎ssessing Ecofriendly Wastes in Removal of Pyrene as a Model of Oil Spills鈥 International Journal of chromatography and separation techniques 2017, 1, J102-106.
- Louka, F. R.; Massoud, S. S.; Haq, T. K.; Henary, M. M.; Vicente, R.; Fischer, R. C.; Mautner, F. A. 鈥淪ynthesis, structural characterization and magnetic properties of onedimensional Cu(II)-azido coordination polymers鈥 Polyhedron. 2017, 138, 177-184.
- Louka, F. R.; Junk, T.; Massoud, S. S., 鈥淒NA Cleavage by Bicompartmental Dinuclear Metal(II) Complexes鈥. J. Biolog. Inorg. Chem. 2017, 22, S137-S137.
- Massoud, S. S.; Louka, F. R.; Ducharme, G.; Fischer, R.; Mautner, F. A.; Vanco,J.; Herchel, R.; Tr谩vn铆膷ek, K.; 鈥淐opper(II) complexes based on tripodal pyrazolyl amines: Synthesis, structure magnetic properties and anticancer activity鈥 Journal of Inorganic Biochemistry. 2018, 108, 36-46.
- Klerks, P. L.; Kascak, A.; Cazan A. M.; Deb Adhikary, N.; Chistoserdov, A.; Shaik,A.; Osman, S. Y.; Louka, F. R. 鈥淓ffects of the razor clam Tagelus plebeius on the fate of petroleum hydrocarbons; a mesocosm experiment鈥 Archives of Environmental Contamination and Toxicology in press 2018.
Awards & Recognition
- April 2018: Eminent Award, Dr. Ray P. Authement Excellence in Teaching, University of Louisiana at 色妹AV, LA
- February 2018: Outstanding Faculty of Universities of Louisiana System 2018.
- Fall 2017 - present: Member in University Senate
- 2017: Awardee of Awardee of Royal Society of Chemistry Books for contents. organization and presentation in ICBIC 18th, Florian贸polis, Brazil.